What causes Dupuytren’s disease?
The cause of Dupuytren’s disease is unknown but may be associated with certain biochemical factors within the involved fascia. The problem is more common in men over age 40 and in people of northern European descent. There is no proven evidence that hand injuries or specific occupational exposures lead to a higher risk of developing Dupuytren’s disease.
What are the symptoms and signs of Dupuytren’s disease?
Symptoms of Dupuytren’s disease usually include a small lump or series of lumps and pits with the palm. The lumps are generally firm and adherent to the skin. Gradually a cord may develop, extending from the palm into one or more fingers with the ring and little fingers most commonly affected. These cords may be mistaken for tendons but they lie between the skin and the tendons, In many cases, both hands are affected although the degree of involvement may vary.
The initial nodules may produce discomfort that usually resolves, but Dupuytren’s disease is not typically painful, The disease may first be noticed because of difficulty placing the hand flat on an even surface, such as a tabletop (see Figure 3). As the fingers are drawn into the palm, one may notice increasing difficulty with activities such as washing, wearing gloves, shaking hands, and putting hands into pockets. Progression is unpredictable. Some individuals will have only small lumps or cords while others will develop severely bent fingers. More severe disease often occurs with an earlier age of onset.
What are the treatment options for Dupuytren’s disease?
In some cases, only observation is needed for nodules and cords that are not contracted. Patients with more advanced contractures may require surgery to improve function.
Various surgical techniques are available to correct finger position. Your treating surgeon will discuss the method most appropriate for your condition based upon the stage of the disease and the joints involved (see Figure 4). The goal of surgery is to improve finger position and thereby hand function. Despite surgery, the disease process may recur and the fingers may begin to bend into the palm once again. Before surgery, your treating surgeon will discuss realistic goals and results.
Specific surgical consideration:
- The presence of a lump in the palm does not mean that surgery is required or that the disease will progress.
- Correction of finger position is best accomplished with milder contractures and contractures that affect the base of the finger. Complete correction sometimes cannot be attained, especially of the middle and end joints in the finger.
- Skin grafts are sometimes required to cover open areas in the fingers if the skin is deficient.
- The nerves that provide feeling to the fingertips are often intertwined with the cords.
- Splinting and hand therapy are often required after surgery to maximize and maintain the improvement in finger position and function.